6. What does increased reticulocyte count indicate in anaemia?
Functioning bone marrow
Low degree of haemolysis
Macrocytic anaemia
Iron deficiency
7. What could cause reduced erythrocyte production?
Bone marrow suppression or disorders
Reduced EPO production (e.g. due to renal failure)
All of the above
Lack of haematinics, e.g. iron, vitamin B12, folate
Anaemia of chronic disease (infection, inflammation, malignancy)
8. Myelodysplasia (lack of healthy blood cells) is a sign of macrocytic anaemia. True or false?
True
False
9. If macrocytic anaemia has been caused due to a dietary lack of vitamin B12 or folate (i.e. its cause is not thought to be neurologically related), which drug would you recommend?
Cyanocobalamin
Hydroxocobalamin
10. What are the symptoms of anaemia?
All of the above
Exertional dyspnoea
Fatigue
Palpitations
11. What are the causes of anaemia of chronic disease?
All of the above
Chronic infection
Malignancy
Rheumatological diseases
12. What is anaemia?
A reduction in haematocrit
All of the above
A reduction in haemoglobin
A reduction in erythrocytes
13. What are the main causes of iron deficiency?
NSAID use
All of the above
Menstrual blood loss
Gastric ulceration
Coeliac disease
14. What are the haemoglobin criteria for men and women (over 18) for anaemia, according to WHO?
<120g/L for both men and women
<130g/L for men, <120g/L for women
<120g/L for men, <130g/L for women
<130g/L for both men and women
15. What is the main dietary source of vitamin B12?
Animal produce only
Greens
Mixture of animal products and greens
16. Normocytic anaemia is caused by anaemia of chronic disease. True or false?
True
False
17. How is autoimmune haemolysis diagnosed?
All of the above
Enlarged spleen
Raised reticulocytes
Strongly positive Coombs test
18. What does thalassemia result in?
Hepatospenomegaly
All of the above
Haemolysis
Ineffective erythropoiesis
19. What additional test can be used to confirm iron deficiency but is difficult to interpret in infection and inflammation?
EPO
Serum ferritin
Reticulocyte count
Vitamin B12 and folate
20. In sickle cell anaemia, haemoglobin S replaces both alpha-globin subunits in haemoglobin A. True or false?