Action potential

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Created by: L.eve
Created on: 19-04-21 22:37

Describe what Luigi Galvani found

Frogs nerve muscle stimulated with electrical charge- transmission is electrical.

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How is an action potential generated?

Neuron cell membrane creates chemicals by pumping ions, ATP is used to fuel the pumps.

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How is charge of membrane potential measured?

The giant squid axiom in a petri dish & saline solution, put electrodes inside & reference electrodes outside then measure the difference,
inside of membrane is negatively charged -70mV which is the resting potential.

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Describe depolarisation

Applying a small positive charge takes away some electrical charge, reducing the membrane potential.

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What is the threshold of excitation?

When a sufficient positive charge is applied, if this happens an action potential is generated.

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What is hyperpolarisation?

This is when the cell returns to normal (resting potential).

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Explain the diffusion of molecules in the cell

Diffusion tries to push chloride into the cell where there's a low conc, but inside is a negative charge so the electrostatic pressure pushes it out, so there's more sodium & chloride extracellular. Diffusion pushes potassium out because of low conc outsi

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Carry on...

Sodium can enter via voltage dependent ion channels which open when threshold is -58mV, membrane potential changes to +40mV, potassium leaves through potassium channels which leads to depolarisation, as potassium leaves negative charge goes back (repolari

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What is the refractory period?

AP cannot be produced at same time, there is a time period which AP isn't generated.

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What is saltatory conduction?

Myelin saves energy, its regenerated at nodes of ranvier.

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Other cards in this set

Card 2

Front

How is an action potential generated?

Back

Neuron cell membrane creates chemicals by pumping ions, ATP is used to fuel the pumps.

Card 3

Front

How is charge of membrane potential measured?

Back

Card 4

Front

Describe depolarisation

Back

Card 5

Front

What is the threshold of excitation?

Back

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Action potential