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Where do non-competitive inhibitors attach themselves to the eznyme?

What happens to the enzyme when a non-competitive inhibitor binds to it?

Is it a permanent change made to the enzymes shape once a non-competitive inhibitor has binded to it?

What is a metabolic pathway?

The enzymes that control a metabolic pathway are usually highly s--------- and in a very precise s-------

How is a steady concentration of each chemical produced maintained?

What is this known as?