"Compare historic drug testing with contemporary drug testing protocols, eg William Withering’s digitalis soup; double blind trials; placebo; three-phased testing." (spec point 2.4.12)
Historic Drug Testing
William Withering's digitalis soup didn't go down too well. Here's the procedure that he followed and why it wasn't so good:
(you will need to know this as a comparison question may ask what is the difference between old and new drug testing procedures)
- Tested on people
=> patients with the disease
=> dosage was estimated
=> many side effects were shown
- Trial and error
=> many people were poisoned because the dosage given was too high!
=> however, others given too low a dosage experienced no benefit whatsoever..
Drug testing today…