Clinical Infectious disease process


Incubation Period

  • Interval between exposure to an infectious agent and the appearance of the first symptoms. 
  • Microorgansim has entered the body, undergone colonisation and begun multiplying.
  • Insufficient numbers to cause symptoms- last several hours/days eg flu 1-2 days
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Prodromal Stage

  • Appearance of initial symptoms which are often mild eg tiredness.
  • Pathogen continues to multiply and individual begins to experience signs and symptoms of illness.
  • Typically a result from activation of immune system. 
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Invasion Period

  • Pathogen is multiplying rapidly, invading further, affecting tissues at site of initial colonisation and other areas.
  • Development of symptoms specifically related to pathogen and symptoms related to inflammatory response.
  • Signs and symptoms of disease are most obvious and severe. 
  • Reaches peak of infection. 
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Convalescence Period

  • Individuals immune and inflammatory systems have in general successful remived infectious agent.
  • Symptoms starting to decline- however disease may be fatal or enter latency phase.
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