Enzymes use the lock and key model to conduct a reaction. The molecule fits into the active site on the enzyme perfectly. Each enzyme has a different shape so it is specific to speeding up a particular reaction.
They are protein molecules, and work best in a human at 37 degrees. If the temperature in the body exceeds 40 degrees enzymes begin to denature, (they lose their shape), this is an irreversible reaction. All enzymes have a specific optimum temperature where the denature. If the temperature falls there are few collisions and the reactions are slow.
If the body temperature exceeds 42 degrees Heat Stoke occurs; hot/dry skin, confusion, dizziness, fast pulse rate and fainting are symptoms. Treatment is to sponge with water, put near a fan, put ice under arms, in groin and on the neck and head.
If body temperature drops below 35 degrees hypothermia occurs; shivering, confusion, slurred speech, loss of co ordination, patient enters a coma if body falls below 30 degrees and death if below 28 degrees. Treat the patient by insulating them, warm them gently with hot drinks and warm towels.
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