Mutations occur at a relatively constant rate so they can be used as molecular clocks
Molecular clocks: The number of genetic differences can predict how long ago two species diverged
The larger the number of differences between two species the longer the time since they diverged from a common ancestor
If the base sequences are similar then few mutations have occurred which means the species only diverged recently
LIMITATIONS
- Different genes or proteins may change at different rates
- The rate of change for a certain gene may differ between two groups of organisms
- May question the accuracy of early predictions based on more recent findings
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