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The Role of Neural Mechanisms
involved in controlling eating and
Eating Behaviour (Booklet 1)…read more

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Dual Centre Model of Eating
· Humans are homeostatic animals
­ Designed to run our bodies in a constant state of
· Have a `feeding centre' to the brain activated
when we are hungry and a `satiety' centre
activated when we are full.…read more

Slide 3

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Hypothalamus ­ the
Dual Centre Model feeding `thermostat' in the
brain regulating eating
The Lateral Hypothalamus (LH) and Ventromedial
Hypothalamus (VMH) act together to maintain
weight balance.
Hypothalamus senses when blood glucose levels
fall, which activates the LH making us feel hungry,
and encourages us to eat.
After eating, we get an increase in blood glucose
due to food intake, which is acknowledged by the
VMH making us feel satiety so we stop eating.…read more

Slide 4

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Signals of declining
blood glucose levels
Lateral Hypothalamus
Satiety ­ feeding
feeding centre
Hunger ­ feeding
Hypothalamus satiety
centre activated.
Signals of rising blood
glucose levels…read more

Slide 5

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· Anand & Brobeck
· Hetherington &
Ranson (1942)
· Extrapolation
· Ignores behavioural
· Reductionism…read more

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Evidence to Support
Anand & Brobeck (1951) Hetherington & Ranson (1942)
Lesioning LH = loss of feeding in rats. Lesioning VMH = rats become obese.
Aphagia Hyperphagia
When damaged, no longer activates when blood When damaged, no longer activates when blood
glucose levels dip. glucose levels rise.…read more

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