The Liver
- Created by: lauren.glendenning
- Created on: 12-04-16 20:02
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- The Liver
- Liver Cells = hepatocytes
- Carry out hundreds of metabolic processes
- Essential it has a very good blood suppy
- Inside the liver is arranged to create best blood supply possible
- Essential it has a very good blood suppy
- Has an important role in homeostasis
- Appear to be relatively unspecialised.
- Simple cuboid shape with many microvilli on their surface
- Many metabloic functions including...
- Protein synthesis
- Transformation and storage of carbohydrates
- Synthesis of cholesterol and bile salts
- Detoxification
- Many metabloic functions including...
- Simple cuboid shape with many microvilli on their surface
- Carry out hundreds of metabolic processes
- Blood flow to and from the liver
- Liver is supplied with blood from two sources
- Oxygenated Blood from heart
- Travels from aorta via hepatic artery into liver
- Supplies oxygen that is essential for aerobic respiration
- Hepatocytes carry out many metabolic processes and many require ATP so ood oxygen supply is needed.
- Supplies oxygen that is essential for aerobic respiration
- Travels from aorta via hepatic artery into liver
- De-oxygenated blood from digestive sytem
- Enters liver from hepatic portal vein
- Blood is rich in products of digestion
- Concentration of various compounds is uncontrolled and blood may contain toxic compounds that have been absorbed in intestine.
- Blood leaves liver via hepatic vein.
- This reaches vena cava and blood returns to normal circulation.
- Blood leaves liver via hepatic vein.
- Concentration of various compounds is uncontrolled and blood may contain toxic compounds that have been absorbed in intestine.
- Blood is rich in products of digestion
- Enters liver from hepatic portal vein
- Oxygenated Blood from heart
- Liver is supplied with blood from two sources
- Arrangement of cells inside the liver
- Cells, blood vessels and chambers are arranged to ensure best possible contact between blood and hepatocytes
- Liver is divided into three parts
- Liver
- Lobes
- Cylindrical lobes
- Lobes
- Liver
- Liver is divided into three parts
- As hepatic artery and hepatic portal vein enter liver they split into smaller vessels
- Vessels run between and parallel to lobules
- Inter-lobular vessels
- At intervals branches from hepatic artery and hepatic portal vein enter lobules.
- Blood from two vessels is mixed and passes along a special chamber called a sinusoid
- Sinusoid is lined by liver cells.
- Sinusoids empty into inter-lobular vessels
- Branches of hepatic vein from different lobules join together to form the hepatic vein, which drains the blood from the liver.
- Blood from two vessels is mixed and passes along a special chamber called a sinusoid
- Vessels run between and parallel to lobules
- Cells, blood vessels and chambers are arranged to ensure best possible contact between blood and hepatocytes
- Functions of liver cells
- Producing bile
- This is released into bile canaliculi (small canals)
- These join together to form bile duct which transports bile to gall bladder.
- This is released into bile canaliculi (small canals)
- Producing bile
- Kupffer Cells
- Specialised Macrophages
- Move about within sinusoids and are involved in breakdown of recycling old red blood cells.
- One of the products of haemoglabin breakdown is billrubin
- Excreted as part of faesces
- Brown pigment in faeces
- Excreted as part of faesces
- One of the products of haemoglabin breakdown is billrubin
- Move about within sinusoids and are involved in breakdown of recycling old red blood cells.
- Specialised Macrophages
- Liver Cells = hepatocytes
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