TB8 Brain & Behaviour Overview; The Remembering Brain

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  • TB8 B&B Overview; The Remembering Brain
    • Lecture 1; Brain systems for memory
      • Amnesia from hippocampal + surrounding area damage
        • Patient HM
        • Patient EP
        • Korsakoff Syndrome
      • Evidence for disassociable memory systems
        • Preservation of some abilities in amnesia
        • The hippocampus and cue binding
    • Lecture 2; The Structure and Function of the Hippocampus
      • Structure of the Hippocampus
        • CA1, CA3 (core)
        • Dendate gyrus (input)
        • Subiculum (output)
        • Surrounding cortical areas
          • Entorhinal cortex
          • Perirhinal cortex
          • Para-hippocampal Cortex
        • Anterior-posterior gradient
      • Cellular Mechanisms
        • Long Term Potentiation (LTP)
          • LTP and memory performance
            • Transgenic Mice
          • Structural changes at the synapse! (CA1, CA3)
          • NMDA Receptors
          • Process & Features
      • Coding in the Hippocampus
        • Cognitive maps and Place cells
        • Theory of Relational Memory/ Framework
        • Recollection v.s familiarity
    • Lecture 3; Memory Represent-ations in the temporal cortex
      • Two systems for episodic and semantic memory
        • Tulving; Episodic VS semantic
        • Squire; Episodic THEN semantic
          • Hippo has 'time-limited' constraints, info transferred to neocortex for consolidation
        • Amnesia studies
        • Semantic dementia pps
        • Single and double disassociation studies
        • Recent stance; the hippo and neo are two distinct, independent, opposing systems
      • Hippocampal and temporal neocortex interaction
        • Computation-al models
      • Transferring information from the hippocampus to neocortex; consolidation
        • Retrograde amnesia gradient
        • Retrieval before consolidation (encoding)
        • Consolidation
          • The role of sleep; SHORT WAVE sleep
            • Experimental manipulations
            • Reactivation during sleep
    • Lecture 4; Control of memory
      • Interference
      • Retrieval of memory
        • Competition of memories
        • Source memory paradigm (what AND when)
      • Selective encoding and retrieval
        • Forgetting
          • Retrieval induced forgetting paradigm
          • Intentional forgetting? (benefits)
          • Traumatic events; PTSD research and suppression
            • Retrieval failures following PFC damage
              • Confabulation
              • Korsakoffs synrome
      • The role of the ventrolateral pFC
        • Encoding
        • Seperating competing memories
        • Retrieval failures following PFC damage
          • Confabulation
          • Korsakoffs synrome
      • Default mode networks
        • Task-negative activation
      • Varieties of semantic impairments
        • SD v.s S aphasia
    • Tutorial; Neuro-physiological data

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