Glycolysis
- Created by: Steff06
- Created on: 25-02-16 16:46
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- Glycolysis:
- Glycolysis takes place in the cell CYTOPLASM. It involes the breakdown of 1 molecule of GLUCOSE to form 2 molecules of PYRUVATE. Net production of 2 ATP.
- 2. GLUCOSE-6-PHOSPHATE --> FRUCTOSE 6 PHOSPHATE
- ISOMERISATION. 1 ATP USED up. Further activation of glucose can occur.
- 1. GLUCOSE --> GLUCOSE-6-PHOSPHATE
- PHOSPHORYLATION which activates the glucose.
- 3. FRUCTOSE-6-PHOSPHATE --> FRUCTOSE-1,6-DIPHOSPHATE
- PHOSPHORYLATION. 1 ATP USED up. Fructose-1,6-diphosphate very unstable and unreactive. Hexose bisphosphate split into 2 separate molecules.
- 4. FRUCTOSE-1,6-DIPHOSPHATE --> TRIOSE PHOSPHATE
- CLEAVAGE of fructose-1,6-biphosphate (splits).
- 5.TRIOSE PHOSPHATE --> PHOSPHOGLYCERATE.
- Steps to convert triose phosphate to pyruvate. OXIDATION removing 2 HYDROGEN atoms from each triose phosphate molecules. ATP FORMED.
- 6. PHOSPHOGLYCERATE --> PYRUVATE
- ATP molecule FORMED for each reaction. HYDROGEN atom pairs accepted by NAD.
- Gross production of ATP = 4, net production of ATP = 2, 2NADH2 (reduced NAD) produced, as NAD has GAINED HYDROGEN.
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