Protein Synthesis

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  • Created by: Lucy
  • Created on: 25-11-12 19:23
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    • Transcription
      • The hydrogen bonds between the two DNA strands break- the DNA uncoils.
        • One of the strands is used as a template to make an RNA copy (antisense strand)
          • Free RNA nucleotides line up alongside the template strand. Once the RNA mononucleotides have paired up with their complementary bases, they're joined together, forming an mRNA molecule.
            • The mRNA moves out of the nucleus through a nuclear pore
              • The mRNA attaches itself to a ribosome in the cytoplasm, where translation takes place.
    • Translation
      • The mRNA attaches itself to a ribosomeand tRNA molecules carry amino acids to the ribosome
        • A tRNA molecule, with complementary bases to the first triplet of bases (codon) on the mRNA attaches itself to the mRNA by complementary base pairing.
          • A second tRNA molecule attaches itself to the next triplet of bases on mRNA in the same way
            • The two amino acids attached to the tRNA molecules are joined together by a peptide bond. The first tRNA molecule moves away, leaving its amino acid behind.
              • A third tRNA molecule binds to the next triplet on the mRNA. Its amino acid binds to the first two and the second tRNA molecule moves away.
                • This process continues, producing a chain of linked amino acids until there's a stop signal on the mRNA molecule
                  • The polypeptide chain moves away from the ribosome and translation is complete.


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