Process of infection

  • Created by: Erin M M
  • Created on: 23-03-22 12:53
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  • Process of Infection
    • Colonisation
      • Infectious  micro- organised live in environments animals + infected humans.
      • Transmitted via direct contact, vectors and direct exposure
      • Aerosolised micro-organisms are primary cause of RTI. Physical contacts also common cause
      • After deposit in receptive environment, micro-organism stabilises adherence to tissue through specific surface receptors
    • Invasion
      • Infectious agents can invade surrounding tissues/ sites
      • Micro-organisms have developed mechanisms to penetrate tissues and avoid hosts specific + non-specific defences
    • Multiplication
      • Need warm, nutrient filled host environment
      • Undergo rapid multiplication. Can replicate within infected cells, + in macrophages+ other cells.
    • Spread
      • Usually produce localised infections that don't spread to other regions.
      • Some are highly infectious and can enter lymphatics, blood + internal organ
      • Spread replies on virulence factors- adhesion mols, toxins + protection against host's inflammatory + immune system
      • Intact immune system = localised infection. Compromised immune system = infection may rapidly spread


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