Process of infection
- Created by: Erin M M
- Created on: 23-03-22 12:53
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- Process of Infection
- Colonisation
- Infectious micro- organised live in environments animals + infected humans.
- Transmitted via direct contact, vectors and direct exposure
- Aerosolised micro-organisms are primary cause of RTI. Physical contacts also common cause
- After deposit in receptive environment, micro-organism stabilises adherence to tissue through specific surface receptors
- Invasion
- Infectious agents can invade surrounding tissues/ sites
- Micro-organisms have developed mechanisms to penetrate tissues and avoid hosts specific + non-specific defences
- Multiplication
- Need warm, nutrient filled host environment
- Undergo rapid multiplication. Can replicate within infected cells, + in macrophages+ other cells.
- Spread
- Usually produce localised infections that don't spread to other regions.
- Some are highly infectious and can enter lymphatics, blood + internal organ
- Spread replies on virulence factors- adhesion mols, toxins + protection against host's inflammatory + immune system
- Intact immune system = localised infection. Compromised immune system = infection may rapidly spread
- Colonisation
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