Narcolepsy

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  • Narcolepsy
    • Symptoms
      • Daytime sleepiness
      • Sleep attacks
      • Cataplexy
      • Sleep paralysis
    • Cause
      • Lack of hypocretin
      • Hormonal changes, stress and infection
    • Thannickal
      • Parkinsons
        • Loss of brain cells
          • 62% of hypocretin cells
        • Similar symptoms
      • Reductionist
    • Arii
      • 16yr old
      • Hypothalamus tumour
        • MRI damage
      • After surgery - narcolepsy
      • CSF compared to control
        • Lower hypocretin levels
          • Disrupted neurotransmissions
      • Case study
    • Nichino
      • Narcoleptic dogs
      • Genetic mutation
        • Hypocretin production
        • Not in humans
      • Animal research
        • Unethical
    • Mignot
      • 16 MZ twins
        • At least one narcoleptic
      • 25% concordance
        • Susceptibility
          • Holism

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