movement of substances across cell surface membrane

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  • Movement of Substances across cell surface membrane
    • Diffusion across membrane depends on:
      • the concentration gradient
      • the size of the molecule
      • the temperature
      • the thickness of the exchange surface
      • the SA of the membrane
    • Simple Diffusion
      • non-polar molecules
      • eg. O2 and CO2
      • very small
      • lipid soluble
    • Facilitated diffusion
      • when the diffusion process is supported or 'facilitated' by proteins
      • two types of protein involved:
        • carrier protein- take in the diffusing molecule (eg. glucose), change shape and release the molecule on the other side of the membrane
        • (ion) channel proteins- formed by proteins with a central pore that enables charged particles(ions) to pass through. Some are permanently open and some are gated
    • Active Transport
      • if mols or ions need to be moved across the membrane against the concentration gradient(low to high conc)
      • energy in the form of ATP is required
      • involves protein carriers (pumps) the substance to be transported binds to the carrier protein
        • as with facilitated diffusion, the carrier changes shape and releases transported substance on the other side of the membrane
      • two key differences to facilitated diffusion:
        • 1) substances are moved against the conc gradient
        • 2) metabolic energy in the form of ATP is required
  • Active Transport
    • if mols or ions need to be moved across the membrane against the concentration gradient(low to high conc)
    • energy in the form of ATP is required
    • involves protein carriers (pumps) the substance to be transported binds to the carrier protein
      • as with facilitated diffusion, the carrier changes shape and releases transported substance on the other side of the membrane
    • two key differences to facilitated diffusion:
      • 1) substances are moved against the conc gradient
      • 2) metabolic energy in the form of ATP is required

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