Lipids
- Created by: Emilyburkee
- Created on: 23-05-22 17:50
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- Lipids
- type
- signaling
- sterols, cofactor pigments
- phosphatdylinstol = c fam in membrane
- broken down to ip3 which binds to ionotropic receptors
- release of CA from SA
- also in neurones - CA for NT relase
- broken down to ip3 which binds to ionotropic receptors
- insulin
- binds to receptors and activates IRS
- recruits pi3k leads vesicles to membrane
- binds to receptors and activates IRS
- phosphatdylinstol = c fam in membrane
- Eicosanoid
- cholesterol = starting Mol
- arachindonca
- protaglyndins and thromboxane and leukotryins
- proteo = vasodialation
- increases temp to help fight infection
- effects blood flow
- thromboxane = blood clotting
- leukotrine
- contraction of smooth muscle
- proteo = vasodialation
- protaglyndins and thromboxane and leukotryins
- arachindonca
- steroid hormones
- cortisol
- released in response to stress, increases gluconeogensis
- corticosterone
- intermed in production of aldosterone
- progesterone
- oesterogen = most stable = more double bond
- cortisol
- cholesterol = starting Mol
- vitamens
- water sol = B AND C
- insol = K,E,D,A
- D = d7chol- UV light breaks bonds = D3
- A= b-caratine = precusor
- cleavage = A1 - Vis light = CIS to TRANs bond
- sterols, cofactor pigments
- storage
- fats Oils
- = energy stroage
- waxes -esters of long chain FA and long chain OH
- PUFAs
- omega 3 - diff naming system - name from double bond
- physical properties
- increase unsaturation = increase solubility
- also decrease melting point
- triglycerides
- fuel stored in adipose = most are mixed FA chains
- energy from fats = more eff then glucose 108 ATP from full oxidation
- hydrophobic = lighter
- partial hydrogenation
- hydrophobic = lighter
- cis to trans bond = CVD
- fats Oils
- structure
- Glycerophopholipids
- x2 FA, glycerol, p diester
- naming =Phosophtyl OH group
- any charge heads + found in membranes
- Galactolipids
- sugar head= polar head with OH
- sphingolipids
- no glycerol
- hydrocarbon- =VDF forces with x2 FA non polar chain
- sphingomyclies
- polar head found in membranes
- gangcosphingolipids
- Polar head = one or more sugars ? Cerebrosides = one sugar ?
- Galactose – plasma membrane of neuronal tissue ? Glucose – plasma membrane of non-neuronal tissue
- Gangliosides
- sterols
- 4 hydrocarbon rings
- ridgid
- cholesterol
- maintains membrane fluidity seperates Phosholipids
- prevents crystalisation
- sterols
- Glycerophopholipids
- signaling
- Synthesis and breakdown
- synth
- breakdown
- type
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