Infection process mindmap kathy h
- Created by: Kathyhark
- Created on: 19-10-22 12:45
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- Process of Infection
- Colonisation
- Reservoirs harbour infectious microorganisms
- Transmitted
- Direct contact eg. *****-oral
- Vectors (indirectly) eg. Insects
- Human-to-human transmission by aerosolized microorganisms in droplets eg.coughing
- physical contact eg.sexual contact
- After transmission microorganism stabilizes adherence to the tissue through specific surface receptors
- Invasion
- Infectious agent invade surrounding area
- Mechanisms are developed to avoid hosts specific and non specific defences (inflammationand immunity)
- Multiplication
- Undergo rapid multiplication
- bacterial pathogens
- replicate in macrophages & other cells
- viral pathogens
- replicate within infected cells (viral pathogens);
- bacterial pathogens
- Warm, nutrient filled host environment
- Undergo rapid multiplication
- Spread
- localized infections: dont spread to other regions of the body
- highly invasive organisms enter lymphatics, blood, internal organs
- Successful spread - relies on virulence factors
- adhesion molecules
- protection against host’s inflammatory and immune system
- toxins
- Host has….
- Intact immune system
- microorganism remains localized
- Immune or inflammatory system compromised
- infection may rapidly spread
- Intact immune system
- Colonisation
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