Genetic explanation for Schizophrenia
- Created by: Georgia
- Created on: 14-04-19 18:32
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- Genetic explanation for schizophrenia
- Outline (A01)
- Closer relation = higher concordance (likely)
- Polygenic - increased vulnerability
- Research methods: twin, family and adoption studies
- Research evidence
- Gottesman and Shields (1982) ;;;; 46% concordance for MZ; 14% concordance for DZ
- Suggests specific gene; genetics has huge influence as MZ > DZ
- Tienari et al (2004) Children of schizophrenia patients still have heightened risk even when adopted
- Suggests environment has no impact as gene already exists
- Gottesman (1991) Schizophrenia more common in biological relatives; closer relation = higher risk
- Gottesman and Shields (1982) ;;;; 46% concordance for MZ; 14% concordance for DZ
- Evaluate (A03)
- Impossible to pinpoint exact gene of cause
- Not 100% concordance rate so must be another factor
- Too reductionist; states must be biology when there is obviously another factor
- Supported by research evidence; higher concordance rate than "normal"
- Small sample sizes in studies; hard to generalise (rare to have twins with schizophrenia)
- Family studies can't separate genes and environment so unreliable
- Use adoption studies to separate
- Too deterministic; states schizo must be inherited with genes when there is only a higher risk
- Outline (A01)
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