Endogenous pacemakers and zeitgebers

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  • Exogenous Zeitgebers
    • external cues that play an important role in regulating biological rhythms helping to synchronise and reset them.
      • EG pacemakers interact with EG zetigebers = entrainment
        • free running is the opposite and the biological clock operates without external cues
          • Light - found to reset the body's main pacemaker the SCN as well as other oscillators located throughout the body.
            • Social cues - daily rhythms appeared to be dictated by social convention.
              • We would eat meal, go to sleep and wakeup at times designated appropriate by our age and social factors.
  • Social cues - daily rhythms appeared to be dictated by social convention.
    • We would eat meal, go to sleep and wakeup at times designated appropriate by our age and social factors.
  • CAMPBELL ET AL - demonstrated that the SCN may not be the main zeitgeber through altering circadian rhythms by shining light on the backs of Ppts knee's.
    • Findings - shifted their rhythms demonstrating that other oscillators must exist that compensate by keeping the biological clocks in tune.
      • May be that blood is the messenger that carries signals across the body
  • Endogenous Pacemakers
    • biological clocks that are generated from within organisms.
      • In mammals, the main pacemaker is a tiny cluster of cells called suprachiasmatic nucleus located in the hypothalamus.
        • SCN receives info on light and sends signals to the pineal gland which then regulates the production melatonin.
          • Induces sleep and inibits brain mechanisms promoting wakefulness.
            • Lights inhibits melatonin production
  • RALPH ET AL - group of hamsters with genetic abnormality that results in a 20 hour circadian cycle
    • SCNs were removed and placed in the brains of experimental group of hamsters
      • experimental group shifted to a 20 hour cycle.
        • Lacked ecological validity

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