Virulence and Sporulation

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  • Created by: Okim34
  • Created on: 20-11-19 19:16
Define colonisation
The presence of bacteria on a body surface without causing disease.
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Define pathogenicity.
Ability of a microbe to cause a disease.
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What are virulence factors?
Microbial products/components that contribute to virulence/ disease.
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State the 4 components of the Kock's postulate.
Germ must be present in every case of the disease, germ must be isolated and grown in pure culture, must cause disease when inoculated in a healthy host, must be re-isolated from the host.
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What is the LD50?
Dose of microbe required to kill 50% of test population.
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What bacteria contain endotoxins in their cell wall?
Gram negative
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How is the middle of the cell detected for sporulation?
SpolllE proteins are evenly distributed across the membrane so there are equal amounts either side of the centre.
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What stimulates SpolllE to move?
Sigma H
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What is the role of sigma F, sigma G and sigma K in sporulation?
Sigma F and G prepare the spore and sigma K strengthens the spore and causes lysis of the mother cell.
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How does a cell decide whether to sporulate?
A two component system
10 of 10

Other cards in this set

Card 2

Front

Define pathogenicity.

Back

Ability of a microbe to cause a disease.

Card 3

Front

What are virulence factors?

Back

Preview of the front of card 3

Card 4

Front

State the 4 components of the Kock's postulate.

Back

Preview of the front of card 4

Card 5

Front

What is the LD50?

Back

Preview of the front of card 5
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