The presence of bacteria on a body surface without causing disease.
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Define pathogenicity.
Ability of a microbe to cause a disease.
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What are virulence factors?
Microbial products/components that contribute to virulence/ disease.
3 of 10
State the 4 components of the Kock's postulate.
Germ must be present in every case of the disease, germ must be isolated and grown in pure culture, must cause disease when inoculated in a healthy host, must be re-isolated from the host.
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What is the LD50?
Dose of microbe required to kill 50% of test population.
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What bacteria contain endotoxins in their cell wall?
Gram negative
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How is the middle of the cell detected for sporulation?
SpolllE proteins are evenly distributed across the membrane so there are equal amounts either side of the centre.
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What stimulates SpolllE to move?
Sigma H
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What is the role of sigma F, sigma G and sigma K in sporulation?
Sigma F and G prepare the spore and sigma K strengthens the spore and causes lysis of the mother cell.
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