Ventilation and perfusion matching

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Define ventilation and perfusion
-Ventilation: process by which 02 and CO2 are transported to and from lungs > in/exhale of air
-Perfusion: blood flow through a region (in this case > lungs)
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Explain why the ventilation/perfusion ratio is important
02 and blood have to in the same place + time to optimise gaseous exchange
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Where is perfusion greatest in the upright lung?
A greater volume of blood travels below heart level (dependent) rather than above heart level (non-dependent regions). This is due to the effects of gravity.
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Where will ventilation be greatest in the upright lung?
-The intrapleural pressure becomes less negative further down the upright lung.
-The apices have greater initial lung volume and reduced compliance than the bases
-Because the bases are more compliant they exhibit greater lung volume changes
-At the bas
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Where are ventilation and perfusion best matched in the upright lung?
Both the ventilation and perfusion gradients increase towards the base of the lung = match in lower 2/3 of lung
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In left side lying where will Va/Q be matched?
In the dependent lower lung (below heart)
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Other cards in this set

Card 2

Front

Explain why the ventilation/perfusion ratio is important

Back

02 and blood have to in the same place + time to optimise gaseous exchange

Card 3

Front

Where is perfusion greatest in the upright lung?

Back

Preview of the front of card 3

Card 4

Front

Where will ventilation be greatest in the upright lung?

Back

Preview of the front of card 4

Card 5

Front

Where are ventilation and perfusion best matched in the upright lung?

Back

Preview of the front of card 5
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