Tuberculosis

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What is the active TB?
the number of bacteria increases producing more tubercules and severley damaging the lung tissue
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What does this lead to?
the break down of alveoli
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What is produced?
large cavities
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What is reduced?
oxygen uptake which can lead to death
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How is TB spread?
droplet infection
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What cells are targeted?
epitehlial cells in the lungs
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What does TB have as a cell wall?
thick waxy cell all
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What is it protected against?
lyzozymes
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What can TB do?
survive inside macrophages and lie dormant until the immune system is weakened
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What two things might a pathologist expect to find in a body of a patient who died of TB?
Presence of TB bacteria and enlarged lymph nodes
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What is the first diagnosis of TB?
skin test, uses protein tuberculin derived from dead acteria, inflammation response
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AB resistance
AB resistance
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What is the selection pressure of AB?
over used
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What happens to the susceptible bacteria?
they are killed
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what do ome bacteria have?
random mutations which produce alleles for resistance
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Where are the AB resistance genes found?
on plasmids
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What happens eventually?
the bacterial population becomes resistant and the AB is no longer effective
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Why does AB resistance build up so rapidly?
bacterial numbers can increase very fast, many AB resistant genes are carried on plasmids which can be passed from one bacterium to another by conjugation
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Other cards in this set

Card 2

Front

What does this lead to?

Back

the break down of alveoli

Card 3

Front

What is produced?

Back

Preview of the front of card 3

Card 4

Front

What is reduced?

Back

Preview of the front of card 4

Card 5

Front

How is TB spread?

Back

Preview of the front of card 5
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