Treatments for Schz

This is for A2 level students studying AQA PSyB3 and 4 

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Conventional Anti-Psychotic Drugs
Neuroleptics
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What are the 2 conventional neuroleptics?
PHENOTHIAZINES and THIOXANTHENES
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Phenothiazines
Clorpromazine
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Thioxanthenes
Navane
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What symptoms do these two drugs treat?
Positive
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How do they work?
They BLOCK the receptors for dopamine, located in the synapses of the neuron, resulting in reduced levels of dopamine
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What do they do?
They reduce the frequency and strength of hallucinations and other +ve symptoms
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How should they be taken?
Regularly and ALL the time
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What did Cole find?
After 6 weeks people taking these drugs showed significant improvement compared to those given a placebo
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Are there any side effects? Are they severe?
Yes and mildly
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What are they?
Akathisia, severe muscle tremors (like those seen in Parkinson's), shuffling of feet when walking, rigid facial expressions, tardive dyskinesia
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Akathisia
restlessness and agitation
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Tardive Dyskinesia
jerky movements of face, tongue and whole body; involuntary chewing, sucking and smacking of lips roughly 10% of people develop this with long-term use
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What are the 2 Atypical antipsychotics?
Clozapine and Risperidone
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Clozapine
+ve and -ve symptoms and is successful with 66% of people within 12 months
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Risperidone
+ve and -ve
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How do they work?
They work less to reduce levels of dopamine and focus more on changing the levels of Seretonin
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What do they do?
They decrease both +ve and -ve symptoms
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Why are they more effective?
They have less side effects- Clozapine is good for people who didn't respond to conventional antipsychotics
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Side effects that can be provoked...
nausea, weight gain, irregular heart beat or sometimes a life threatening condition where the levels of white blood cells in the body decrease dramatically
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Card 2

Front

PHENOTHIAZINES and THIOXANTHENES

Back

What are the 2 conventional neuroleptics?

Card 3

Front

Clorpromazine

Back

Preview of the back of card 3

Card 4

Front

Navane

Back

Preview of the back of card 4

Card 5

Front

Positive

Back

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