Toxicity of elements

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1. Which of these statements is incorrect about alcohol intoxication?

  • Ethyleneglycol - which is used for antifreezing/sweet taste.
  • Methanol causes metabolic acidosis and brain damage
  • Glycolic acid causes causes renal failure and oxalic acid metabolic acidosis
  • 90% of ethanol is oxidised in the liver by alcohol dehydrogenase
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2. Which coordinate ion does BAL not prefer to form a ligand with?

  • Fe3+, Al3+, Ca2+
  • Hg2+,As3+, Sb3+
  • ,As3+, Sb3+ Ni2+

3. Which of these elements resemble K+?

  • Mn (EE) increased excitability of CNS
  • Ti - degeneration of all cell types, including neuronal damage
  • Se (and essential element) causes blocking of dehydrogenases
  • As (AsH3 or As2O3) binds to S-H in enzymes

4. Which of these metal toxication statement is correct?

  • Mercury is an Irreversible inhibtor cathelochomines. Enzymes dependant on selenium
  • Mercury can be treated through Dialysis
  • Cadmium has (cumulative phenomenon) and accumalates in kidney and liver irreversible replacing Zn
  • Ba- can lead to hear failure. BaSO4 used in xrays
  • Cu causes inherited defect in ceruloplasmin synthesis. Results in poor Fe2+ absorption(radicals can then form fenton)
  • Be blocks enzymes that utilise Mg2+ and can damage skin/lungs
  • Cu accumalates in brain, liver, kidney. Cirrohosis, loss of coordination, mental disorders.

5. Which metal ion does EDTA tend to form a ligand with?

  • Ca2+, Pb2+
  • Fe3+, Al3+
  • Cu2+, Hg2+


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