thromb

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  • Created by: hadar
  • Created on: 22-11-15 11:10
Streptokinase- mechanism of action
cleaves the Arg-Val bond in plasminogen to produce active plasmin. converts inactive plasminogen molecules into active plasmin.
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Streptokinase- therapeutic affect
Plasmin in turn degrades the fibrin matrix of the thrombus- reperfusion to tissue and restoration of blood flow
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Urokinase- mechanism of action
cleaves the Arg-Val bond in plasminogen to produce active plasmin. converts inactive plasminogen molecules into active plasmin.
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Urokinase- therapeutic affect
Plasmin in turn degrades the fibrin matrix of the thrombus- reperfusion to tissue and restoration of blood flow
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Tenecteplase- mechanism of action
cleaves the Arg-Val bond in plasminogen to produce active plasmin. converts inactive plasminogen molecules into active plasmin.
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Tenecteplase- therapeutic affect
degrades the fibrin matrix of the thrombus-reperfusion to tissue and restoration of blood flow
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Warfarin- mechanism of action
inhibits vitamin K reductase- depletion of the reduced form of vitamin K
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Warfarin- therapeutic affect
decreased prothrombin levels and a decrease in the amount of thrombin generated
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Dalteparin- mechanism
potentiates the activity of ATIII, inhibiting the formation of both factor Xa and thrombin.
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Dalteparin- therapeutic affect
antithrombin binding site that is essential for high affinity binding to the plasma protein antithrombin (ATIII)
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Other cards in this set

Card 2

Front

Plasmin in turn degrades the fibrin matrix of the thrombus- reperfusion to tissue and restoration of blood flow

Back

Streptokinase- therapeutic affect

Card 3

Front

cleaves the Arg-Val bond in plasminogen to produce active plasmin. converts inactive plasminogen molecules into active plasmin.

Back

Preview of the back of card 3

Card 4

Front

Plasmin in turn degrades the fibrin matrix of the thrombus- reperfusion to tissue and restoration of blood flow

Back

Preview of the back of card 4

Card 5

Front

cleaves the Arg-Val bond in plasminogen to produce active plasmin. converts inactive plasminogen molecules into active plasmin.

Back

Preview of the back of card 5
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