The Cytoskeleton 0.0 / 5 ? BiologyCell BiologyUniversityNone Created by: SarahCreated on: 27-03-17 11:24 Why does intermediate filaments have no polarity? they assemble in an antiparallel way 1 of 30 what are basal bodies? like centrioles (for MTs) for cilia or flagella 2 of 30 what is present in the lag phase of microfilaments (actin filaments)? nucleating factors 3 of 30 what do nucleating factors do to actin filaments? overcome the energetically unfavourable step when forming a trimer 4 of 30 which component of the cytoskeleton is not found in yeast/fungi? intermediate filaments 5 of 30 what do the associated proteins for intermediate filaments do? cross linking 6 of 30 what is type 3 of intermediate filaments? desmin muscle 7 of 30 what does the gelsolin actin binding protein do? caps/severs or nucleates 8 of 30 what role does microfilaments (actin filaments) have in fertilisation? acrosomal head penetrates the egg by extending the acrosome with MFs 9 of 30 what are the ring complexes on the centrosome made up of gamma (Y) tubulin 10 of 30 what end is far away from the centrosome? + end 11 of 30 structure of basal bodies? triplet MTs 3 rings of MTs fused together. Inner smaller one, connecting proteins between them 12 of 30 what is type 1 and 2 of intermediate filaments? epithelial keratins 13 of 30 what are the major roles of MTs? cell shape, movement and division 14 of 30 what is the structure of MTs? heteropolymer of alpha+beta tubulin. Dimers and 13 protofilaments 15 of 30 how heavy is MTs heteropolymer? 50kD 16 of 30 what are the cell type specific actins for smooth muscle? alpha smooth muscle and gamma smooth muscle 17 of 30 what is the critical concentration of polymerisation? rate of addition = rate of loss 18 of 30 what happens in dynamic instability? all ATP (in actin) is converted to ADP its shrinks lose the GTP cap as nor wnoufh GTP tubulin to maitain 19 of 30 what does the actin binding protein thymosin do? monomer binding decreased assembly 20 of 30 what is the cell type specific actin for striated muscle? alpha skeletal and alpha cardiac 21 of 30 what do Intermediate filaments do? maintain structure and shape, protects nucleus 22 of 30 where is the exposed GTP in microtubules, what subunit? both alpha and beta subunit has GTP bound 23 of 30 which subunit in MTs has the exposed GTP? beta 24 of 30 what are MTs? 24nm diamater hollow tubes 25 of 30 what protein is MT made from? tubulin 26 of 30 what microtubule associated proteins are there? map2, Tau, and dyenin and kinesin 27 of 30 what do TAU and MAP2 do? assembly promoting 28 of 30 how many amino acids is actin filaments? 375 29 of 30 is actin heteromeric or homomeric? homomeric 30 of 30
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