The Cell Lecture 7

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  • Created by: saraht83
  • Created on: 01-05-16 15:00

1. What happens during elongation?

  • ribosome moves along mRNA in 5'-to-3' direction, polypeptides grow from N terminus, charged tRNA's bring amino acids to the ribosome sequentially, specificity provided by the anticodon interaction + the accuracy of aminoacyl-tRNA synthetases
  • complex forms, initiator tRNA charged with methionine + small ribosomal subunit bound to mRNA triggers beginning of translation
  • presence of stop codon in A site of ribosome, completed protein released
  • more than 1 ribosome moves along mRNA at one time
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2. What are the three phases of translation?

  • initiation, elongation, termination
  • initiation, electron conductance, transcription
  • transfer, elongation, transcription
  • transfer, electron conductance, termination

3. What happens during initiation?

  • more than 1 ribosome moves along mRNA at one time
  • complex forms, initiator tRNA charged with methionine + small ribosomal subunit bound to mRNA triggers beginning of translation
  • presence of stop codon in A site of ribosome, completed protein released
  • ribosome moves along mRNA in 5'-to-3' direction, polypeptides grow from N terminus, charged tRNA's bring amino acids to the ribosome sequentially

4. What is a polysome?

  • 1 ribosome moves along mRNA at one time, multiple copies of same protein made from single mRNA
  • 1 ribosome moves along mRNA at one time, making one copy of protein
  • more than 1 ribosome moves along mRNA at one time, multiple copies of same protein made
  • more than 1 ribosome moves along mRNA at one time, making one protein copy

5. What four components does translation require?

  • ribosomes, tRNA, activating enzymes + mRNA
  • cytoplasm, DNA, activating substrates + mRNA
  • ribosomes, DNA, activating enzymes + mRNA
  • cytoplasm, tRNA, activating substrates + mRNA

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