TB9 BB Lecture 2; How do we control a movement?

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  • Created by: mint75
  • Created on: 02-05-16 14:56

1. In terms of basal ganglia damage, which of these causes Huntingtons?

  • Unilateral damage to subthalamic nuclei. Unwanted movements
  • Degeneration of striatum. No inhibition of thalamus, resulting in overexcitability and unwanted movements
  • Lack of dopamine increases activity of direct pathway. Tonic inhibition of thalamus and less excitation of cortex. Difficulties starting and stopping movements
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2. What connection type does GABA facilitate?

  • Modulatory connections
  • Inhibitory connections
  • Excitatory connections

3. All movements are executed in the context of...

  • Action specificity
  • Orientation
  • Posture
  • Muscle tone

4. Which of these is the circuit for readout?

  • Cerebellar cortex --> deep cereb nuclei --> superior cereb penduct --> ventrolateral PMC
  • Frontal motor areas --> pons --> cerebellar cortex

5. The cortex and caudate and putamen share?

  • Excitatory connections
  • Inhibitory connections
  • Both excitatory and inhibitory connections

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