TB9 BB Lecture 2; How do we control a movement?

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  • Created by: mint75
  • Created on: 02-05-16 14:56

1. In terms of basal ganglia damage, which of these causes Huntingtons?

  • Unilateral damage to subthalamic nuclei. Unwanted movements
  • Degeneration of striatum. No inhibition of thalamus, resulting in overexcitability and unwanted movements
  • Lack of dopamine increases activity of direct pathway. Tonic inhibition of thalamus and less excitation of cortex. Difficulties starting and stopping movements
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2. Which deep structure is responsible for reading out?

  • Basal ganglia
  • Pons
  • Medulla
  • Superior Colliculus

3. In the indirect pathway of timing and movements, what is inhibited less causing more stimulation of the substantia-nigra/globus pallidus resulting in no movement?

  • Thalamus
  • Corticospinal tract
  • Subthalamic nuclei
  • Substantia-nigra/globus pallidus

4. The cortex and caudate and putamen share?

  • Excitatory connections
  • Inhibitory connections
  • Both excitatory and inhibitory connections

5. Which of these is the circuit for receiving input?

  • Frontal motor areas --> pons --> cerebellar cortex
  • Cerebellar cortex --> deep cereb nuclei --> superior cereb penduct --> ventrolateral PMC


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