6. Why is there interest in Williams syndrome as a model for developmental disorders?
Because of its well defined genetic pathology
Because it has specific behavioural deficits and global cognitive deficits
Because it disassociates with other disorders
Because it has specific cognitive and behavioural deficits
7. Do WS children significantly differ from typically developing 4-5 year olds when matched for mental age in motion/form processing?
No
Yes
8. Does WS show expressive or telegraphic language?
Expressive as opposed to telegraphic in Down syndrome
Telegraphic as opposed to expressive in Down syndrome
9. What would you expect to see in social interactions from a WS sufferer?
Socially engaging, poor TOM, cant distinguish lies from irony and negative socially inappropriate behaviour
Socially engaging, poor TOM, cant distinguish lies from irony and positive socially inappropriate behaviour
Socially engaging, good TOM, can distinguish lies from irony and positive socially inappropriate behaviour
Socially unengaging, poor TOM, cant distinguish lies from irony and negative socially inappropriate behaviour
10. How does neuroconstructivism explain the spatial cognitive deficits in WS?
WS individuals impaired in spatial cognition as dorsal stream develops unusually bc WS individual does not detect visuo-spatial properties
Genes missing in WS also involved in anatomical development of dorsal stream pathways
11. Which cognitive phenotypes are represented in the DD between WS and autism?
Space
Social cognition
Language
Problem solving
12. How does cognitive genetics explain the spatial cognitive deficits in WS?
Genes missing in WS also involved in anatomical development of dorsal stream pathways
WS individuals impaired in spatial cognition as dorsal stream develops unusually bc WS individual does not detect visuo-spatial properties
13. What does neuroconstructivism emphasise?
The role of gene expression THROUGH developement. Early cognitive profile inferred from adult end state. Fractionation of strengths and weaknesses across domains,disregard of environment
The role of genes in coding cognitive abilities. Are specific cognitive modules selectively affected?
14. What does the local-processing bias hypothesis suggest about the nature of WS visual-spatial disorder?
WS have issues with the global form of objects but do not struggle with fine detail
WS have issues with the local features of objects but do not struggle with global arrangement
15. Which cognitive phenotypes are represented in the DD between WS and Down syndrome
Space
Problem solving
Social cognition
Language
16. Which of these is not a cognitive phenotype in WS?
Intact spatial and numerical skills
Impaired spatial and numerical skills
Intact language, face recog and social interaction
IQ range from 40-90
17. What does cognitive genetics emphasise?
The role of genes in coding cognitive abilities. Are specific cognitive modules selectively affected?
The role of gene expression THROUGH developement. Early cognitive profile inferred from adult end state. Fractionation of strengths and weaknesses across domains,disregard of environment
18. What do WS show unusual performance in as measured by word fluency task?
Vocabulary
Enrichment of linguistic affect
Syntax
Grammar
19. How doesneuroconstructivism explain WS?
The adult state of the language system may be mature but not 'intact'. Language is atypical in many ways, WS informs about the low level processes of language
The genes coding for language skills are intact, other developmental disorders are impaired on these genes.
20. Which of these is NOT present in the socio-cognitive deficit profile of WS?
Excessive eye contact with novel adult > parent
Lack of social inhibition
Telegraphic and evaluative language excessively used
Expressive and evaluative language excessively used
WS perform at extremely high level (higher than controls) on face recognition