Synaptic transmission

HideShow resource information
What is synaptic transmission related to?
1 of 42
What opens when the AP reaches the presynaptic terminal?
Calcium ion channels open
2 of 42
What is the first fundamental process?
Manufacture - intracellular biochemical processes
3 of 42
What is the second?
Storage in vesicles
4 of 42
What is the third?
Release by AP
5 of 42
The fourth?
Interact with postsynaptic receptors and diffuse across synapse
6 of 42
The fifth?
Inactivation - breakdown/re-uptake?
7 of 42
What does ACH stand for and what is it?
Acetylcholine and it is a transmitter substance
8 of 42
What gates ion channels relating to postsynaptic membrane effects
9 of 42
What are the channels on the postsynaptic membrane sensitive to?
Neurotransmitter substances
10 of 42
Name the three fast neurotransmitters
11 of 42
Name the three neuromodulators
12 of 42
What is Dale's principle?
"each neuron uses a different neurotransmitter"
13 of 42
Why is Dale's principle not strictly true?
GLU and GABA use different modulators and modulatory systems can use different modulators
14 of 42
What is an endorphin?
A pepticle with opiate-like effects
15 of 42
What do endorphins and opiates inhibit?
Substance p, released by pain receptors
16 of 42
What do local anaestethics such as procaine and lignocaine do?
Block AP and Na+ channels, well absorbed by mucous membranes
17 of 42
What is ACH affected by?
Nicotine, Spider poison, poison from arrows (curare) and nerve gas
18 of 42
Which things that affect ACH are agonists?
Nicotine and arrow poison (curare)
19 of 42
Which affects release?
Spider Poison
20 of 42
How does nerve gas effect ACH?
Blocks breakdown
21 of 42
Where is ACH widely used?
Brain and spinal chord
22 of 42
Where does noradrenaline act as a transmitter?
23 of 42
How do stimulants effect it?
Increase release and blocks re-uptake
24 of 42
How do MAO inhibitors effect it?
Block release
25 of 42
How do anti-depressants effect it?
Block re-uptake
26 of 42
What is dopamine important in?
Basal ganglia
27 of 42
How do anti-psychotics affect it?
Acts as receptor blocker
28 of 42
How do amphetamines/cocaine effect it?
increase release and block re-uptake
29 of 42
How do anti-parkison's drugs e.g. L-DOPA effect it?
Increase manufacture
30 of 42
What is the function of serotonin?
Diverging projection in brain and supplies structure
31 of 42
How do SSRI's affect it?
Effect reuptake
32 of 42
What does SSRI stand for?
Selective Serotonin Re-uptake Inhibitor
33 of 42
How does MDMA effect it?
Suggestions that it may be neurotoxic
34 of 42
How may hallucinogens e.g. LSD effect it?
They act as a receptor agonist
35 of 42
Why does L-DOPA work for Parkinson's disease?
Blocks release of dopamine
36 of 42
What is GABA?
Main inhibitory transmitter
37 of 42
Which two types of drugs have inhibitory effects at GABA receptors?
anti-convulsants and anti-anxiety (benzodiazepenes and valium)
38 of 42
Which type of drugs potentiate GABA effects?
Anaesthetics and barbiturates
39 of 42
What is the main problem for drug design?
Brain region for different function uses many different neurotransmitters, leads to side effects
40 of 42
What can L-DOPA cause in high doses?
41 of 42
What can DA blockers or antipsychotics cause in high doses
42 of 42

Other cards in this set

Card 2


What opens when the AP reaches the presynaptic terminal?


Calcium ion channels open

Card 3


What is the first fundamental process?


Preview of the front of card 3

Card 4


What is the second?


Preview of the front of card 4

Card 5


What is the third?


Preview of the front of card 5
View more cards


No comments have yet been made

Similar Psychology resources:

See all Psychology resources »See all Neuroscience resources »