Structure and Function of Biological Membranes 0.0 / 5 ? BiologyCell and Molecular BiologyUniversityNone Created by: LucyLaaCreated on: 13-10-18 18:58 What is the plasma membrane? A cell boundary that controls movement in and out of cells 1 of 22 What do organelle membranes do? Divide cytoplasm into compartments? 2 of 22 What are endosomes? Membrane-bound vesicles (endocytosis = reverse exocytosis) 3 of 22 What is an Acinar cell? Outward facing cells of the pancreas that produce and transport digestion enzymes 4 of 22 Give an example of a plasma membrane adaptation in the eye Long protusions for the high sensitivity area 5 of 22 What is a polarised cell? Where the composition of the apical membrane differs from the basal lateral membrane 6 of 22 Why do we study membranes? It helps us to understand a diverse range of behaviours 7 of 22 Name 3 fundamental properties of membranes Barrier; flexible and self-repairing ; selectively permeable; continuous 8 of 22 What are optical tweezers? What do they demonstrate about the membrane? A laser beam that can pick up a piece of membrane and move it along a tubule --> demonstrates elastic capabilities 9 of 22 What are the basic components of a membrane? Lipids (phospholipids, cholesterol and sterols); proteins; carbohydrates (glycoproteins and glycolipids 10 of 22 What property makes phospholipids effective components of the bilayer? Amphipathic --> polar head, hydrophobic tail 11 of 22 True or false: Phospholipids can only be saturated False --> Phospholipids can be cis unsaturated, and kinked 12 of 22 Are linear hydrocarbon chains always an even or odd number? Even (12-22) 13 of 22 Name a major membrane phospholipid Phosphatidyl-ethanolamine; phosphatidyl-serine; phosphatidyl-choline; sphingo-myelin 14 of 22 Which phospholipid is negatively charged and important for apoptosis? Phosphatidyl-serine 15 of 22 Is the proportion of phospholipids the same in every membrane? No. 16 of 22 What does cholesterol do to a membrane? Stabilises it and prevents phospholipids coalescing together 17 of 22 What is the structure of cholesterol? Polar head group; rigid steroid ring structure; non-polar hydrocarbon tail 18 of 22 What are phosphoinositides used for? Protein interaction 19 of 22 How can you form liposomes? Sonificate cells 20 of 22 What are liposomes used for? Drug delivery; delivery of DNA/RNA into cells for GM; Cosmetic industry 21 of 22 Is the bilayer neat or messy? Very messy --> fluidity inherent in a muddled structure 22 of 22
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