Structural Abnormalities

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Weinburger et al (1979)
Use of CAT scans and report ventricular size was greater in group of 58 individuals with chronic schizophrenia compared to 56 people
1 of 12
Andreason (1988)
Studied MRI scans of schizophrenia and non-schizophrenic people. They found that in schizophrenics, their ventricles were 20% to 50% larger than those in the control group
2 of 12
Vita et al (1988)
CAT scans showed that 33% of the 124 schizophrenics has moderate to severe atrophy and found males were more likely to have it
3 of 12
Luchins et al (1979)
Compared CAT scans of 80 normal right handed people to 57 right handed schizophrenics. They found that there was a increase frequency of 'reversal' in both frontal and occipital lobes in those with schizophrenia, but only those with no other atrophy.
4 of 12
Disanto et al (2012)
Those born in Jan, were more likely diagnosed w/ schizophrenia. Due to expectant mothers more likely exposed to flu virus & vitamin D deficiency while pregnant
5 of 12
Johnstone et al (1976)
Schizophrenic has enlarged ventricles, linking to reduction in temporal and frontal lobe. Cell loss in temporal lobe (cognitive & emotional function) associated w/ negative symptoms
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Buchbaum (1990)
MRI scans show brains with schizophrenia had abnormalities in prefontal cortex
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Raine et al (1997)
No difference in brain structures, notably in those associated with mental illness
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McCarley et al (1999)
Claims presence of enlarged ventricles in schizophrenics is most reliable finding due to use of brain scans
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Lyon et al (1981)
Suggest that once diagnosed &being treated w/ antipsychotics, the medication causes structural abnormalities
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Roy et al (1998)
Those diagnosed w/ bipolar disorder & schizoaffective are also found to have enlarged ventricles. Links to overlapping symptoms
11 of 12
Mathalon et al (2003)
Structural abnormalities in schizophrenic people are due to neurodegenerative and neurodevelopmental factors
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Other cards in this set

Card 2

Front

Studied MRI scans of schizophrenia and non-schizophrenic people. They found that in schizophrenics, their ventricles were 20% to 50% larger than those in the control group

Back

Andreason (1988)

Card 3

Front

CAT scans showed that 33% of the 124 schizophrenics has moderate to severe atrophy and found males were more likely to have it

Back

Preview of the back of card 3

Card 4

Front

Compared CAT scans of 80 normal right handed people to 57 right handed schizophrenics. They found that there was a increase frequency of 'reversal' in both frontal and occipital lobes in those with schizophrenia, but only those with no other atrophy.

Back

Preview of the back of card 4

Card 5

Front

Those born in Jan, were more likely diagnosed w/ schizophrenia. Due to expectant mothers more likely exposed to flu virus & vitamin D deficiency while pregnant

Back

Preview of the back of card 5
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