Stress and Illness - immune systemm

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Who investigated short term stressors; exam stress?
Kiecolt-Glaser et al
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What did Keicolt et al do?
Carried out a natural experiment - took blood samples of medical students one month before and one month during exams (low/high stress) - assessed immune system by measuring NK cell activity and PPs did questionnaire
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What did Keicolt-Glaser find?
NK significantly reduced in second blood sample suggesting short term stressors reduce immune system functioning increasing vulnerability to illness (those with highest stress had lowest NK count)
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Who conducted a study on healing and stress?
Marucha et al. inflicted a punch biopsy in the mouth of students in holidays/3 days before exams
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What did Marucha find?
That the wound 3 days before exams took up to 40% longer to heal
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What experiment did Keicolt-Geiser et al. do on long term stress?
She found that a blister wounds on the arms of marital couples took longer to heal when they had negative rather than supportive discussions
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Who said a correlation between stress and illness is hard to establish?
Lazarus
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Why is stress hard to correlate?
Other life factors (genetics, diet) Health is fairly stable and takes a long time to change, long term stress needs continuous measurement over long periods of time and this is expensive and time consuming
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What research goes against short term stressors?
Evans et al. looked at an antibody - arranged for students to give talks to other students (mild stressor) these showed an increase in the antibody, levels decrease during alevels. This suggests stress has two effects = up/down regulation
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Card 2

Front

What did Keicolt et al do?

Back

Carried out a natural experiment - took blood samples of medical students one month before and one month during exams (low/high stress) - assessed immune system by measuring NK cell activity and PPs did questionnaire

Card 3

Front

What did Keicolt-Glaser find?

Back

Preview of the front of card 3

Card 4

Front

Who conducted a study on healing and stress?

Back

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Card 5

Front

What did Marucha find?

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