Specialist Community Public Health Nurse

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PHARMACOLOGY
HOW DRUGS AFFECT THE BODY OR COMBAT INFECTIOUS ORGANISM
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PHARMACOKINETICS
WHAT THE BODY DOES TO THE DRUG
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PHARMACODYNAMICS
WHAT THE DRUG DOES TO THE BODY
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BIO-AVAILABILITY
IS THE FRACTION OF THE DRUG THAT REACHES THE SYSTEMIC CIRCULATION
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THERAPUETIC WINDOW
DIFFERENCE BETWEEN MAXIMUM TOLERATED
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BIO-AVAILABILITY OF ANTIBIOTICS
100 PERCENT (100 % )
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BIO-AVAILABILITY OF ASPIRIN AND PARACETAMOL
100 PERCENT (100 % )
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BIO-AVAILABILITY OF NYSTATIN , GTN AND LATULOSE
ZERO PERCENT ( 0 % )
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ABSORPTION IS ....
DRUGS ARE PERCIEVED BY THE BODY TO BE HARMFUL (TOXINS) OR FOODS STRATEGIES ARE EMPLOYED TO OVERCOME THIS
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WHAT EFFECTS ABSORPTION....
1. CHANGE IN ROUTE (ORAL) 2 CHANGE IN THE FORMULATION (PATCH) 3. PHYSICAL CHEMICAL PROPERTIES OF THE DRUG
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WHAT EFFECTS ABSORPTION....
4. STABILITY IN ACID 5. RESISTACE TO STOMACH ENZYME 6. EASE OF ABSORPTION THROUGH STOMACH WALL 7. REDUCED GASTRIC ACID SECRETION
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WHAT EFFECTS ABSORPTION....
8 REDUCED GASTRIC INTESTINAL BLOOD FLOW 9. CONGESTIVE CARDIAC FAILURE (CCF) 10. DRUG INTERACTIONS
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WHAT EFFECTS ABSORPTION...
1. CHANGE ROUTE, 2. DIFFERING DRUG RE COATING, 3. ROUTE OF ADMINSTRATION, 4. THERAPUETIC OBJECTIVES LOCAL OR SYSTEMIC EFFECTS
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WHAT EFFECTS DISTRIBUTION
7. PLACENTAL BARRIER - DRUG MAY GO INTO FOETUS OR STAY WITH MOTHER 8. BLOOD BRAIN BARRIER - STOPS PASSAGE OF LIPID SOLUBLE DRUGS IN THE CENTRAL NERVOUS SYSTEM 9. WATER SOLUBILITY - GENTAMICIN DIFFERING DOSES
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WHAT EFFECTS DISTRIBUTION.....
1. PHYSICAL PROPERTIES OF DRUG 2. BLOOD FLOW TO ORGAN 3. PROTEIN BINDING THAT EFFECTS DRUG 4. ALBUMIN LEVELS WILL EFFECT PROTEIN BINDING 5. HIGH LIPID SOLUBILITY, DRUG WILL NOT GO INTO FAT
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WHAT EFFECTS DISTRIBUTION...
6. DRUG INTERACTION - DISPLACEMENT OF ONE BOUND DRUG WITH ANOTHER 7. PLACENTAL BARRIER - DRUG MAY GO INTO FETUS OR STAY WITH MOTHER 8. BLOOD BRAIN BARRIER - STOPS PASSAGE OF LIPID INSOLUBLE DRUG IN CNS 9. WATER SOLUBILITY - GENTAMICIN
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DISTRIBUTION IS.....
A REFLECTION OF THE AMOUNT OF DRUG LEFT IN THE BLOOD STREAM AFTER ALL THE OF IT IS ABSORBED
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Other cards in this set

Card 2

Front

PHARMACOKINETICS

Back

WHAT THE BODY DOES TO THE DRUG

Card 3

Front

PHARMACODYNAMICS

Back

Preview of the front of card 3

Card 4

Front

BIO-AVAILABILITY

Back

Preview of the front of card 4

Card 5

Front

THERAPUETIC WINDOW

Back

Preview of the front of card 5
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