Solutions and solubility

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Q H Y S E Y N V L Q J U H Y X L T L X S N
L L B T X Y D A H D C Q H P S D D V P A U
Y D W N R Y A U D F M G H C A B K O A U W
S P D E M E Q G K J M X I J T T L O X F W
N X I V P Q O E L U L T C S O Y A I G Q L
I H S L I A O F E N C N I D M A E F J T R
R Q S O C L H M F E C N P O U E B S U X R
T W O S E K X L T O K S R L N Y U O D D F
X U L O T S N U M C K P Q X G O G X S H G
E O U C I U E M O N H R V K H N B D A A K
D A T Y V D O N I I L A Y P I D G V W E P
O I I E Y N D U C W M L R T H T O N U M F
L Q O M I I M S B R O O L C Q Q F V F X N
C C N O T V O S E J M A A E K E S A I B W
Y W N I A L I Q E A S M F S L J J T Y S N
C T O S V X N M O X I X X N T P P E D K B
U N C A V Q D G H E G L B X T N Q U E B G
S U T U C O M P L E X A T I O N C W D G N
Y E J Q F C U C B B R P E B I Q C V U R I
S M H E C I F P G X V B Q Q G L M A P N W
R O P L Y S Q L A M T B K F T K T D N O O

Clues

  • Adding an electrolyte to an aqueous solution of a non-electrolyte, decreasing the solubility of the non-electrolyte (7, 3)
  • An ion that is already contained within a solution and increasing its concentration leads to a decrease in solubility (6, 3)
  • Do symmetrical and compact drugs or amorphous drugs go into solution more easily? (9)
  • The conditions where absorption is faster than dissolution, and C (conc of bulk solution) doesn't exceed 10% of Cs (conc of solution at solid/solvent boundary) (4, 10)
  • The general name of a water-miscible solvent that is added to alter the polarity of another solvent to ultimately increase its solubility (2, 8)
  • The mixing of two crystalline solids together which results in a mixture that has a lower melting point than either of the components individually (9)
  • The process of the removal of a solute molecule from a solid, the creation of a cavity in a solvent, and the insertion of the solute molecule in the cavity (11)
  • The solvates recrystallise into a new form when the solvent is removed (11, 8)
  • What is the interaction of a poorly soluble drug with a soluble material to form a soluble macromolecular complex called? (must also be reversible) (12)
  • What is the name of hollow cylindrical molecules in a cyclic arrangement where part or all of the drug molecule is inserted into the hollow central cavity of the molecule? (13)

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