blood vessels , GIT, reproductive system, in the eye
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2 layers of smooth muscle
circular, longitudinal
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where often has 3rd layer
oblique layer in stomach
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Features of s muscle
tonic and phasic contractions, each cell contracts as single cells, slow contraction, cells are intercolated by myosin filaments
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sources of Ca for smooth
SR + ECF (via opening of Ca channels influx)
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contraction process -
ca binds to camoldulin - froms complex. This complex activates the enzyme MLCK. myosin becomes phosphylated , cross bridging occurs. when ca levels fall contraction stops
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