Sliding Filament Model/Power Stroke

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1. In the first stage of 'The power stroke', myosin head groups on the myosin filaments form cross brigdes with the surrounding filaments by

  • Attaching themselves to the binding sites on actin
  • ADP and Pi, this entire process repeats, causing the sarcomere to contract fully
  • Overlap more with the thick filament. This stage is specifically known as the power stroke
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2. The pattern of banding on myofibrils is caused by the sarcomeres, these are the smallest

  • A large number of myofibrils within the sarcoplasm they, like fibres, exhibit a striated pattern under the microscope
  • Contractile units of the muscle and are arranged end to end for the entire length of the myofibril
  • Groups of muscle fibres surrounded by connective tissue containing blood vessels and nerves

3. A cross bridge is

  • The name given to the attatchment formed by a myosin head binding to a binding site on an actin filament
  • Wound around the actin, reinforcing it

4. In the third stage of 'The power stroke', the myosin heads use the energy in ATP to detach from the actin, the head group moves backwards as ATP is hydrolysed to

  • Overlap more with the thick filament. This stage is specifically known as the power stroke
  • ADP and Pi, this entire process repeats, causing the sarcomere to contract fully
  • Attaching themselves to the binding sites on actin

5. In the second stage of 'The power stroke', upon binding to the actin, the myosin heads change shape, pulling the thin actin filaments towards the centre of the sarcomere, so they

  • Overlap more with the thick filament. This stage is specifically known as the power stroke
  • ADP and Pi, this entire process repeats, causing the sarcomere to contract fully
  • Attaching themselves to the binding sites on actin

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