Sean Roe L1- endocrine and pit

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  • Created by: Rscottqub
  • Created on: 01-04-19 14:35
endocrine cells comared to exo
rely on blood to carry hormones to organ of target
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exocrine
have ducts which are part of a vessel - located near the organ of target
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types of cell communication (5)
1. neural 2. paracrine 3. autocrine 4. endocrine 5. neurocrine
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Neural
almost immediate
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paracrine
depends on length of diff path since it relies on diffusion
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autocrine
cells stimulate themselves/communicate with itself
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endocrine
use bloodstream to communicate with cells all over the body - can be v slow - but can result in whole body effect
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neurocrine
exclusively produced by pit. v quick. uses bloodstream
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Mechanism of action of hormones (2)
1. hormone binds to receptor on cells which is specific to hormone 2. hormone penetrates the CM and binds to receptor inside cytoplasm/on mito and causes change in function of the cell
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how do we know which mechanism of action?
dependent on nature of the hormone , only lipid soluble hormones can pass thru the CM
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main diff between ant and post pit
ant. pit has endocrine cells , post pit doesnt
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post pit
hormones are secreted straight into blood
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ant pit
involves 2 hormones , 1 to activate the endocrine cells to secrete the 2nd
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which pit secretes neurohormones
post pit
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abbreiv RH
releasing hormone
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SH
stimulating hormone
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post pit secretes
ADH , oxytocin
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deficiency in secretions can lead to
Diabetes incipidus - lack of ADH . Lack of growth hormone - dwarfism
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panhypopituitarism
lack/deficiency of a single hormone
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Xs secretion
ie giantism etc
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Other cards in this set

Card 2

Front

exocrine

Back

have ducts which are part of a vessel - located near the organ of target

Card 3

Front

types of cell communication (5)

Back

Preview of the front of card 3

Card 4

Front

Neural

Back

Preview of the front of card 4

Card 5

Front

paracrine

Back

Preview of the front of card 5
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