Schizophrenia

1. A drug that binds to and alters the activity of a receptor. (e.g. amphetamine) (7)
4. Bizarre beliefs that seem real to the patient: can be paranoid, may involve inflated beliefs about their power & importance. (9)
6. Negative symptom: Inability to initiate or persist in goal-directed behaviour. (9)
7. A positive symptom of sz: the patient believes their mind or body is under the control of someone/thing else. (11, 2, 7)
9. Bizarre, unreal perceptions of the environent. Can be visual, auditory, tactile or olfactory. (14)

2. A drug that binds to a receptor but which does not alter the activity of the receptor. (e.g. chlorpromazine) (10)
3. Negative symptom of sz: poverty of speech. (6)
5. What percentage of patients using conventional antipsychotics relapsed in Davis et al's meta-analysis? (55% on placebo relapsed) (8)
8. According to the DSM-IVR the diagnosis of sz requires at least a one month duration of 2 or more ___ symptoms. (8)
10. Negative symptom: reduction in the range and intensity of emotional expression. (9, 10)

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