Schizophrenia and antipsychotics 0.0 / 5 ? PharmacyCentral Nervous SystemUniversityNone Created by: SamDaviesCreated on: 01-05-19 17:51 Type of symptoms where there is the presence of abnormal thoughts or behaviours, e.g. delusions and hallucination Positive 1 of 15 Type of symptoms where there is the absence of normal behaviours, e.g. decreased expression of emotion, social withdrawal, cognitive impairment Negative 2 of 15 Hyperactivity of this pathway underlies schizophrenia Dopaminergic 3 of 15 The class of first generation neuroleptics which include the drugs chlorpromazine and fluphenazine Phenothiazines 4 of 15 The class of first generation neuroleptics which include the drugs haloperidol and droperidol Butyrophenones 5 of 15 The class of first generation neuroleptics which include the drugs flupenthixol and clopenthixol Thioxanthines 6 of 15 The group of side effects associated with first generation neuroleptics Extrapyramidal 7 of 15 The class of second generation neuroleptics which include the drugs sulpiride and amisulpride Dopamine antagonists 8 of 15 The class of second generation neuroleptics which include the drugs clozapine and olanzapine MARTAs 9 of 15 The class of second generation neuroleptics which include the drugs risperidone, zotepine, sertindole, quetiapine and aripiprazole Serotonin dopamine antagonists 10 of 15 The first-line drug for treatment-resistant schizophrenia Clozapine 11 of 15 The side effect associated with clozapine which prevents first-line use Agranulocytosis 12 of 15 The positive symptoms of schizophrenia may be generated by the overactivity of this pathway Mesolimbic 13 of 15 The negative symptoms of schizophrenia may be generated by the underactivity of this pathway Mesocortical 14 of 15 Long-acting depot injections give sustained-release preparations lasting 1-4 weeks through this type of administration Intramuscular 15 of 15
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