Schizophrenia 0.0 / 5 ? PsychologySchizophreniaUniversityNone Created by: francesca_321Created on: 17-05-17 15:05 how many people does schizophrenia affect? 1% of the world population 1 of 36 What was the Term coined by Bleuler? Split mind, A break with reality 2 of 36 What is the concordance rate of developing schizophrenia? 48% 3 of 36 What is Clorpromazine? A dopamine antagonist - Diminishes positive 4 of 36 What is a dopamine agonist? Amphetamine - Induce positive effects 5 of 36 Why do agonists induce positive symptoms Ventral tegmental area to nucleus accumbens and amygdala 6 of 36 What does activity of dopamine neurons in the accumbens do? Reinforce behaviour 7 of 36 What did Snyder suggest about schizophrenics? Report elation at the start of a schizophrenic episode 8 of 36 What did Fibiger suggest? Paranoid delusions are caused by activity in amygdala (Amygdala is involved with learning emotional response 9 of 36 What do Schizophrenics with negative and cognitive symptoms exhibit? Neurological damage 10 of 36 When is a person more likely to have schizophrenia? Born in spring months and winter 11 of 36 What happens if there is a viral infection during the 2nd trimester of pregnancy? Schizophrenia occurs 12 of 36 If schizophrenia has a biological basis it should what? Correlate with other biological traits 13 of 36 What did Schiffman do? He analysed minor abnormalities measured in 265 Danish children, 1991 adult psychiatric outcome data collected 14 of 36 What did Schiffman suggest was the association with schizophrenia? Prenatal distubrances in 1st or 2nd trimester, when combined with second hits, birth complications and family rearing increase chance of schizophrenia 15 of 36 What did the low number of schizophrenia patients lead to? Restricts generality of results (also patient account for 10% of sample?? should be =1% 16 of 36 What did Davis et al suggest? Monochronic concordance is 60%, dichoronic concordance = 10.7% 17 of 36 What is depression? Low energy levels, adhedonia, loss of appetite for food and sex, sleeping problems, constipation 18 of 36 What is mania? Euphoria, delusional poor attention span, lack of sleep, self important 19 of 36 Bipolar disorder? Alternating periods of mania and depression, 1% of the population afflicted at some point in their life, Equally frequent in men and women 20 of 36 What is the characteristics of unipolar disorder? Depression without mania, 2 or 3 three times more likely in women than men, some cases of mania without depression but rare 21 of 36 What did Rosenthal find? 10 times more likely to suffer from affective disorders if a close relative also does 22 of 36 What did Gershon et al (1976)? MZ concordance = 69%, DZ concordance = 13% 23 of 36 What did Price suggest? Concordance is the same whether the twins are raised apart or together 24 of 36 What is MOA? Enzyme that destroys monoamines in PoSN, Serotonin, dopamine, norepinephrine 25 of 36 What is the action of Iproniazid? Inhibits MOA (thus increase serotonin, dopamine, norepinepherine) 26 of 36 What is the action Tricyclic anti depressant? Agonist of just serotonin and norepinerpherine 27 of 36 What does it do? Inhibits reuptake of neurotransmitter by terminal buttons 28 of 36 What is SSRIs (eg Prozax, Ciralopram) Agonist of just serotonin, inhibit reuptake of Serotonin 29 of 36 What is monoamine hypothesis? Depression caused by low activity on monoamine neurons, dopamine agonists do not relieve depression, serotonin and norepinepherine 30 of 36 What does Reserpine do? USed to treat high blood pressure, side effect: depression 31 of 36 WHat is lithium used to treat? Mania 32 of 36 Why it works is not what? Fully understood, possibly stabilises serotonin releases 33 of 36 What are side effects: Diuresis, hand tremors, weight gain, thirst 34 of 36 What does Vogel suggest? Preventing REM sleep acts as an antidepressant, 35 of 36 What did Scherschlicht suggest? Examined effects of antidepressants, all reduced rem sleep, most increased slow wave sleep 36 of 36
Comments
No comments have yet been made