Respiratory drugs

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  • Created by: SamDavies
  • Created on: 02-05-19 00:49
An example of a short-acting beta 2 agonist other than tertbutaline. These drugs bind to β-adrenoreceptors on the smooth muscle of the bronchi. β2 receptors are also present in myocardial tissue, so side effects include tachycardia and palpitations.
Salbutamol
1 of 12
An example of a long-acting beta 2 agonist other than formeterol. These should only be given to pts already taking an inhaled corticosteroid
Salmeterol
2 of 12
An example of a muscarinic antagonist other than tiotropium. These block the M1, M2 and M3 receptors in bronchial smooth muscle. They are used in the management of asthma combined COPD
Ipratropium
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An example of a methylxanthine which has a narrow therapeutic index, side effects similar to the CNS hyperactivity of caffeine, and has interactions with erythromycin, smoking, heart failure, pneumonia
Theophylline
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An anti-IgE monoclonal antibody used in severe persistent allergic-type asthma. It is used as an add on therapy
Omalizumab
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An oral glucocorticoid treatment which can be given short-term (e.g. 10 days) in severe exacerbations of asthma or COPD
Prednisolone
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This drug class reverses mucosal oedema, decreases the inflammatory cascade and inhibits the release of leukotrienes. They reduce the hyperesponsiveness of airway smooth muscle to bronchoconstrictor stimuli
Corticosteroid
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The following drugs are examples of this drug class: beclometasone, budesonide, fluticasone, mometasone. They can cause oral candidiasis
Inhaled corticosteroid
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The following are side effects of this drug class: osteoporosis, increased risk of infection, increased risk of diabetes, hypertension, hypokalemia, glaucoma, peripheral oedema
Corticosteroid
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An example of a mast cell stabiliser which prevents the release of antihistamines. The dose is 3-4 times daily. Should not be given in acute exacerbations of asthma
Sodium cromoglycate
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An example of a leukotriene receptor antagonist (leukotrienes are part of the inflammatory cascade so these are antiinflammatories)
Monteleukast
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An oral phosphodiesterase 4 inhibitor used to reduce exacerbations in patients where severe chronic bronchitis. Cannot be used for acute relief from bronchospasm but does reduce inflammation in COPD
Roflumilast
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Other cards in this set

Card 2

Front

An example of a long-acting beta 2 agonist other than formeterol. These should only be given to pts already taking an inhaled corticosteroid

Back

Salmeterol

Card 3

Front

An example of a muscarinic antagonist other than tiotropium. These block the M1, M2 and M3 receptors in bronchial smooth muscle. They are used in the management of asthma combined COPD

Back

Preview of the front of card 3

Card 4

Front

An example of a methylxanthine which has a narrow therapeutic index, side effects similar to the CNS hyperactivity of caffeine, and has interactions with erythromycin, smoking, heart failure, pneumonia

Back

Preview of the front of card 4

Card 5

Front

An anti-IgE monoclonal antibody used in severe persistent allergic-type asthma. It is used as an add on therapy

Back

Preview of the front of card 5
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