Renal Physiology

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  • Created by: Molly
  • Created on: 05-06-14 11:30
How much filtrate is reabsorbed in the proximal tubule?
60-70%
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How much filtrate is reabsorbed in the loop of Henle?
20-255
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K+ secretion is via which cells?
Principle cells
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K+ reabsorption is via which cells?
Intercalated cells
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What controls these processes?
Aldosterone
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Which nuclei make ADH/Vasopressin?
Supraoptic and paraventricular
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Where is ADH/Vasopressin released from?
Posterior pituitary gland
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Which receptors do ADH/Vasopressin bind to?
V2
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Where are these receptors located?
The basolateral cell membranes of the principle cells in the distal part of the nephron
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What does ADH/Vasopressin do?
Increaase water and urea permeability
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What increases ADH/Vasopressin output?
Haemorrhage, increase in ECF osmolarity, sleep, fright and excerise
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What decreases ADH/Vasopressin output?
Alcohol
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What does Aldosterone increase the reabsorption of?
Na+, Cl- and water
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What does Aldosterone increase the secretion of?
K+
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What does Aldosterone increase the excretion of?
H+
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What's the sensation of thirst induced by?
Stimulation of hypothalamic osmoreceptors
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Hypovolaemia is detected by what?
Cardiovascular stretch receptors
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What is pituitary (central) diabetes inspidus?
No/reduced synthesis or release of ADH from hypothalamo-pituitary axis
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What is nephrogenic (peripheral) diabetes inspidus?
Lack of response by kidney to circulating ADH
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What can an overproduction of ADH lead to?
Hypervolaemia, hyponatraemia --> water intoxication
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What are the symptoms of an overproduction of ADH?
Headache, convulsions, coma and death
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Card 2

Front

How much filtrate is reabsorbed in the loop of Henle?

Back

20-255

Card 3

Front

K+ secretion is via which cells?

Back

Preview of the front of card 3

Card 4

Front

K+ reabsorption is via which cells?

Back

Preview of the front of card 4

Card 5

Front

What controls these processes?

Back

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