Regulation of Transcription and Translation

?
  • Created by: bencook7
  • Created on: 26-01-15 11:59
What can affect the expression of genes?
Other molecules in the cell e.g. Oestrogen
1 of 12
How does Oestrogen affect transcription?
It binds to a transcription factor called Oestrogen receptor, forming an Oestrogen-oestrogen receptor complex
2 of 12
Where is this complex found and where does it move to?
From the Cytoplasm into the nucleus
3 of 12
What happens in the nucleus to this complex?
It binds to specific DNA sites near the start of the target gene
4 of 12
What can the complex act as?
Either as an activator, e.g. helping RNA polymerase, or as a repressor, e.g. blocking RNA polymerase
5 of 12
What does it depends on if the complex is either a repressor or an activator?
It depends on the type of cell and the target gene
6 of 12
What does the level of Oestrogen in a particular cell affect?
The rate of transcription of target genes
7 of 12
What can siRNA interfere with?
Both the transcription and translation of the genes
8 of 12
How does siRNA affects the translation of a gene?
Through a mechanism called RNA interference
9 of 12
In the cytoplasm and during the mechanism, what does siRNA and associated proteins bin too?
The target mRNA
10 of 12
What do the proteins do to the mRNA in the mechanism, called RNA interference?
They cut up the mRNA into sections so it can no longer be translated
11 of 12
What does the siRNA do to the specific gene?
It prevents the expression of the specific gene as its protein can no longer be made during translation
12 of 12

Other cards in this set

Card 2

Front

How does Oestrogen affect transcription?

Back

It binds to a transcription factor called Oestrogen receptor, forming an Oestrogen-oestrogen receptor complex

Card 3

Front

Where is this complex found and where does it move to?

Back

Preview of the front of card 3

Card 4

Front

What happens in the nucleus to this complex?

Back

Preview of the front of card 4

Card 5

Front

What can the complex act as?

Back

Preview of the front of card 5
View more cards

Comments

No comments have yet been made

Similar Biology resources:

See all Biology resources »See all DNA, genetics and evolution resources »