Regulation of Transcription and Translation

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  • Created by: bencook7
  • Created on: 26-01-15 11:59
What can affect the expression of genes?
Other molecules in the cell e.g. Oestrogen
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How does Oestrogen affect transcription?
It binds to a transcription factor called Oestrogen receptor, forming an Oestrogen-oestrogen receptor complex
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Where is this complex found and where does it move to?
From the Cytoplasm into the nucleus
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What happens in the nucleus to this complex?
It binds to specific DNA sites near the start of the target gene
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What can the complex act as?
Either as an activator, e.g. helping RNA polymerase, or as a repressor, e.g. blocking RNA polymerase
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What does it depends on if the complex is either a repressor or an activator?
It depends on the type of cell and the target gene
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What does the level of Oestrogen in a particular cell affect?
The rate of transcription of target genes
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What can siRNA interfere with?
Both the transcription and translation of the genes
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How does siRNA affects the translation of a gene?
Through a mechanism called RNA interference
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In the cytoplasm and during the mechanism, what does siRNA and associated proteins bin too?
The target mRNA
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What do the proteins do to the mRNA in the mechanism, called RNA interference?
They cut up the mRNA into sections so it can no longer be translated
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What does the siRNA do to the specific gene?
It prevents the expression of the specific gene as its protein can no longer be made during translation
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Other cards in this set

Card 2

Front

How does Oestrogen affect transcription?

Back

It binds to a transcription factor called Oestrogen receptor, forming an Oestrogen-oestrogen receptor complex

Card 3

Front

Where is this complex found and where does it move to?

Back

Preview of the front of card 3

Card 4

Front

What happens in the nucleus to this complex?

Back

Preview of the front of card 4

Card 5

Front

What can the complex act as?

Back

Preview of the front of card 5
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