molecules that move into the nucleus from the cytoplasm and stimulate transcription
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How does oestrogen switch on a gene and therefore start translation?
1. binds with receptor site on transcriptional factor. 2. changes shape of receptor molecule. 3. releases inhibitor molecule so transcriptional factor can now enter nucleus and bind with DNA
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What does siRNA stand for?
small interfering RNA
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Does siRNA prevent or activate gene expression?
prevent
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How does siRNA work?
a strand of siRNa combines with an enzyme & guides it to and mRNA molecule & pairs up with its complimentary bases. The enzyme then cuts the mRNA into smaller sections. the mRNA now cannot be translated and the gene is not expressed.
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Name 2 ways siRNA could be used for medical/scientific purposes
used to identify the role of genes in a biological pathway, or block genes that cause diseases.
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Card 2
Front
How does oestrogen switch on a gene and therefore start translation?
Back
1. binds with receptor site on transcriptional factor. 2. changes shape of receptor molecule. 3. releases inhibitor molecule so transcriptional factor can now enter nucleus and bind with DNA
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