Regulation of blood glucose

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What is the exocrine function of the pancreas?
Cells manufacture and release digestive enzymes.
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What is the endocrine function?
Islets secrete hormones into the blood.
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What is the role of the pancreatic duct?
To carry fluid containing enzymes into the 1st part of the small intestine.
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What are the enzymes that the fluid contains?
Amylase, trypsinogen, lipase.
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What does the fluid also contain and what is its role?
Also contains sodium hydrogencarbonate which is alkaline and neutralises the contents of the digestive system.
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Describe what happens when the glucose levels are too low
Detected by alpha cells which secrete glucagon. Glucagon binds to receptor on hepatocytes.
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What are the effects of glucagon?
Glycogenolysis, use of more fatty acids in respiration and gluconeogenesis.
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What is glycogenolysis?
Conversion of glycogen to glucose.
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What is gluconeogenesis?
Production of glucose by conversion of amino acids and fats.
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What happens when blood glucose concentration is too high?
Detected by beta cells in Islets of Langerhans which secrete insulin. Insulin binds to receptors on hepatocytes.
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What does the binding cause?
Binding causes adenyl cyclase to be activated which converts ATP to cAMP.
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What does cAMP do?
cAMP activates enzymes.
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What is the effect of insulin of cells?
More glucose channels are placed on the cell surface membrane so more glucose enters the cell.
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What is the consequence of more glucose entering the cell?
Glycogenesis, more glucose converted into fats and used in respiration.
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What is the effect of this?
Increased entry of glucose through channels reduces blood glucose concentration.
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What is glycogenesis?
Glucose converted to glycogen for storage.
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Other cards in this set

Card 2

Front

What is the endocrine function?

Back

Islets secrete hormones into the blood.

Card 3

Front

What is the role of the pancreatic duct?

Back

Preview of the front of card 3

Card 4

Front

What are the enzymes that the fluid contains?

Back

Preview of the front of card 4

Card 5

Front

What does the fluid also contain and what is its role?

Back

Preview of the front of card 5
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