Psychopharmacology of Reward 0.0 / 5 ? PsychologyNeroscieceUniversityNone Created by: ksjvsbaCreated on: 17-01-16 16:34 Olds and Milner ICSS of rats 1 of 10 Brain Reward Circuitry Anterior Bed Nucleus of mFB -> ventral tegemental area -> nucleus accumbens -> ventral palladium 2 of 10 Pecina (2003) preserves 10% DAT resulting in 70% elevated dopermine. enhanced wanting but not show greate liking to sweet tastes 3 of 10 Cues predicting reward... elicit fluctuations in DA release, nucleus accumbens shell 4 of 10 Beyene (2010)- cue evoked DA release in NAc shell caries as a function of RM 5 of 10 Cocaine increases DA in NAc by blocking reuptake- extreme wanting 6 of 10 Endocannabinoids (CHeer) signalling via CB1R was necessary for DA release induced by cocoain, nicotine and ethanol. 7 of 10 Anadamide.. (Williams and Kirkham 2002) increases appetitive feeding behviour and increased consummatory behaviour. similar to THC 8 of 10 Opiods -mediate food liking reduce food intake and make previously nice meals not nice. 9 of 10 Naxalone - antagonist affect food intake but leave other feeding related parameters unaffected and other general behviours unaffected. 10 of 10
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