Physiology lecture 10 0.0 / 5 ? BiologyControl of blood pressureUniversityNone Created by: willmiddlehamCreated on: 03-04-15 15:19 Where are baroreceptors located? Carotid sinus, aortic arch 1 of 16 Baroreceptor afferent pathway Glossopharyngeal/ vagus 2 of 16 Baroreceptor efferent pathway Sympathetic - heart/blood vessels Parasympathetic - heart 3 of 16 Where is the baroreceptor control centre located? Medulla of brain stem 4 of 16 What do baroreceptors do? Respond to stretch of artery due to change in BP, increase stretch = fire more APs 5 of 16 Effect of posture on BP Redistribution ~500ml of blood from intrathoracic vessels to veins of lower limbs - gravity 6 of 16 When you stand up..... venous pooling, causes VR to DECREASE, CO to DECREASE and BP to DECREASE this activates baroreceptors 7 of 16 What is the response to standing up? Reflex tachycardia, +ve inotropic effects, vasoconstriction - increase TPR 8 of 16 What is postural hypotension? When a decrease in BP of 20 mmHg after 1 minute - lead to syncope 9 of 16 Whittier the long term blood volume regulators? 1) Atrial pressure receptors - ANP 2) Renal responses - fluid excretion 10 of 16 What does atrial natriuretic peptide do? Promotes Na+ and water excretion 11 of 16 What does renin-angiotensin do? Stimulates aldosterone release and decreased Na+ excretion 12 of 16 Nam 4 cortico-hypothalamic influences 1) Fight/flight 2) Diving 3) Thermo-regulatory 4) Sexual 13 of 16 Explain the response of BP to stress (symp.) Increase sympathetic cholinergic - skeletal muscle. Smooth muscle relaxes and decrease TPR 14 of 16 Explain the response of BP to stress (parasymp.) Increase in parasympathetic output - heart. Decrease HR. 15 of 16 Response of BP to stress (both symp and para) Rapid decrease in BP - reduced flow to brain - loss of consciousness (vasovagal syncope) 16 of 16
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