Pharmacology of the NMJ - Medicine BM5 NLM1

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1. Complete the following sentence: Maintaining whole muscle contraction requires...

  • ...a series of asynchronous muscle fibre twitches
  • ...an annoying thing
  • ...a partial response
  • ...a series of synchronous of muscle fibre twitches
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2. Neostigmine is a medium acting anticholinesterase. What is the duration of action of neostigmine?

  • 2-4hrs
  • 4-6hrs
  • 6-8hrs
  • 1-2hrs

3. Identify the symptom most commonly assoicated with organophosphate poisoning.

  • Bursting eyeballs
  • Respiratory muscle paralysis
  • Increased urine output
  • Tachycardia

4. Although Botulinum toxin is used cosmetically, what disease is it also used to help manage symptoms?

  • Muscular Dystrophy
  • Cerebral Palsy
  • Parkinsons
  • Alzheimers

5. If Vecuronium is given to a patient with Myasthenia Gravis, what will happen to the transmission block comparative to a person without MG on Vecuronium

  • Enhanced
  • It will be reduced to such an extent that the patient with MG will spontaneously combust
  • Reduced
  • No difference

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