Pharmacology of the NMJ - Medicine BM5 NLM1

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1. Complete the sentence: Whole muscle contraction is...

  • ...a summation of the muscle fibre twitches
  • ...a partial response
  • ...an annoying thing
  • ...a series of synchronous muscle fibre twitches
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Other questions in this quiz

2. What is a Mini End Plate Potential (MEPP)?

  • A large depolarization that does not reach the threshold value, caused by ACh fusing without an axonal signal
  • A small depolarization that reaches the threshold value, caused by ACh fusing without an axonal signal
  • A small depolarization that does not reach the threshold value, caused by ACh fusing without an axonal signal
  • A small depolarization that does not reach the threshold value, caused by AChE fusing without an axonal signal

3. True or false: Neostigmine is a quaternary ammonium so does not cross the blood-brain barrier, whereas Physostigmine is a tertiary ammonium so will cross the blood-brain barrier?

  • Neither
  • I'm sorry I haven't got a clue
  • True
  • False

4. Metabolism of ACh in the synaptic cleft is rapid. Approximately what speed does it take place at?

  • 10x10^6 molecules per msec
  • 5x10^6 molecules per msec
  • 2.5x10^6 molecules per msec
  • 1x10^6 molecules per msec

5. Does a Mini End Plate Potential (MEPP) cause a muscle twitch?

  • No
  • Yes
  • Possibly
  • Sometimes

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