Pharmacology of the NMJ - Medicine BM5 NLM1

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  • Created by: Lechiayim
  • Created on: 10-02-14 18:02

1. Select the option which identifies the most common characteristic of Myasthenia Gravis at the cellular NMJ level.

  • The number of ACh receptors on the post-synaptic membrane are reduced
  • The number of ACh vesicles released from the presynaptic knob is increased
  • The number of ACh receptors on the post-synaptic membrane are increased
  • The number of ACh vesicles released from the presynaptic knob is decreased
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Other questions in this quiz

2. Suxamtheonium stimulates Nicotinic Type II receptors at the NMJ and causes muscle contraction. What happens after this?

  • Both the muscle fibre and end plate remain depolarized(causing flaccid paralysis)
  • The muscle fibre will relax but the end plate remains depolarized (causing flaccid paralysis)
  • Both the muscle fibre and end plate relax (causing flaccid paralysis)
  • The muscle fibre will remain depolarized but the end plate relaxes (causing flaccid paralysis)

3. What is the speed of onset of Suxamethonium?

  • 1-2mins
  • 10-20mins
  • 2-4mins
  • 4-10mins

4. Which two substances combine to form ACh in the presynaptic terminal?

  • Acetyl CoA & Choline
  • Acetate & Choline
  • Acetic Acid & Cholinesterase
  • Acetyl CoA & Cholinesterase

5. Select the correct example of an organophosphate.

  • Malathion
  • Tetrodotoxin
  • Edrophonium
  • Physostigmine

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