Pharmacology lecture 2

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G-protein coupled: what does Gs do?
Activates adenylyl cyclase and Ca2+ channels
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G-protein coupled: what does Gi do?
Inhibits adenylyl cyclase. Activates K+ channels
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G-protein coupled: what does Gq do?
Activates phospholipase C
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Nuclear receptors: Class I. Where is it located? What does it form? What are the agonists?
Located in cytoplasm, form homodimers, ligands are endocrine (steroids)
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Nuclear receptors: Class II. Where is it located? What does it form? What are the agonists?
Located in nucleus, form heterodimers, ligands are lipids (fatty acids)
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Card 2

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G-protein coupled: what does Gi do?

Back

Inhibits adenylyl cyclase. Activates K+ channels

Card 3

Front

G-protein coupled: what does Gq do?

Back

Preview of the front of card 3

Card 4

Front

Nuclear receptors: Class I. Where is it located? What does it form? What are the agonists?

Back

Preview of the front of card 4

Card 5

Front

Nuclear receptors: Class II. Where is it located? What does it form? What are the agonists?

Back

Preview of the front of card 5

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