Pharmacology lecture 2 0.0 / 5 ? BiologyDrug interactionsUniversityNone Created by: willmiddlehamCreated on: 27-03-15 12:32 G-protein coupled: what does Gs do? Activates adenylyl cyclase and Ca2+ channels 1 of 5 G-protein coupled: what does Gi do? Inhibits adenylyl cyclase. Activates K+ channels 2 of 5 G-protein coupled: what does Gq do? Activates phospholipase C 3 of 5 Nuclear receptors: Class I. Where is it located? What does it form? What are the agonists? Located in cytoplasm, form homodimers, ligands are endocrine (steroids) 4 of 5 Nuclear receptors: Class II. Where is it located? What does it form? What are the agonists? Located in nucleus, form heterodimers, ligands are lipids (fatty acids) 5 of 5
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